HeartDrug Research LLC
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Publications

Books/Book chapters :

  1.                  Axelrod VG, Serebruany VL, Medvedev MV. Use of transcutaneous PaO2 for estimation of breathing in the newborns undergoing negative  pressure.In : “Actual aspects of human adaptive reactions in experimental and clinical practice”. V.V.Gavrushov (Editor) Moscow,  Progress” 1986; pp. 126-148.|

2.                  Serebruany VL, Medvedev MV. Ultrasound antenatal diagnosis of urinary tract malformations in fetus. In : “Congenital and hereditary diseases in children.” Moscow/Berlin, M.S. Ignatova, Z.Schults (Editors) 1988; pp. 148-154.

3.                  Levitzky SV, Barkagan LZ, Serebruany VL.  “Thrombophilia in children : Pathogenesis; Diagnosis; Pharmacology.” Practical guide for doctors. 1989, Moscow “Medicina”, 83p.

4.                  Serebruany V.L. “Hi, America !” First legal immigration guide for Russians. DIANE Publishing, Inc. 1995; 256p.

5.                  Gurbel PA, Kologie F, Serebruany VL, Mergner WJ.  Myocardial cell injury during ischemia and reflow.  In : Principals of Medical Biology. Volume 13. Bittar EE, Bittar N.  (Editors) JAI Press, Inc. 1998, pp. 127-166.

Original Articles

A. Published :

 1.         Burakova VB, Musikantova VS, Sydorova TA, Serebruany V.L. Clinical  and morphological correlations in premature newborns with intraventricular hemorrhage. Pediatria 1985; 9 : 10-13.

2.         Medvedev M.V., Serebruany  V.L., Machinskaya E.A. Antenatal diagnosis of Ebshtein syndrome using echocardiography. Pediatria 1986; 11 :  68-69.

3.         Medvedev MV, Serebruany VL, Axelrod VG. Antenatal ultrasound diagnosis of combined heart defect in fetus. Vopr. Ochr. Mater. & Det  1987; 1 : 72-73.

4.         Serebruany VL, Barkagan LZ  Hemostatic abnormalities and pharmacology of the nephrotic syndrome in childhood. Pediatria 1987; 2 : 91-94.

5.         Serebruany VL, Ignatova MS, Degtyareva EM. Thrombophilia in children with the nephrotic syndrome. Pediatria 1989; 1 : 49-53.

6.         Svetlov SI, Serebruany VL Platelet-activating factor: biochemical and pathophysiological aspects. Pathophysiol  Exper Ther 1989; 1 : 70-75.

7.         Svetlov SI, Burova VYa, Serebruany VL, Veltischev YE. Morphological changes in pulmonary and kidney tissues, induced by intravenous PAF and blocked by verapamil injections. Bull Exper Biol Med, 1989; 58 : 276-279.

8.         Serebruany VL, Christenson MJ, Pescetti J, McLean R H. Hypoproteinemia in the hemolytic-uremic syndrome of childhood. Pediatric Nephrol 1993; 7 : 72-73.

9.         Herzog WR, Atar D, Gurbel PA, Vogel RA, Schlossberg ML, Serebruany VL.  Effect of magnesium infusion on platelet  aggregation in swine. Magnes Res 1993; 4:349-353.

10.       Gurbel PA, Anderson RD, MacCord CS, Scott HJ, Serebruany VL, Herzog WR.  Accelerated intravenous dosing of recombinant tissue plasminogen      activator causes rapid but unstable reperfusion in canine model of acute myocardial infarction.  Cor Artery Dis 1994; 5:929-936.

11.       Atar D, Serebruany V, Poulton J, Godard J, Sneider A, Herzog W.  Effects of magnesium supplementation in a porcine model of myocardial ischemia and reperfusion. J Cardiovasc Pharm 1994; 24: 603-611.

12.       Herzog WR, Schlossberg ML, Mortensen SA, Serebruany VL.  Effect of  Coenzyme Q10 supplementation on platelet aggregability in swine. CoQ10 Res Biol Med 1995; 3 : 5 - 8.

13.       Gurbel PA, Serebruany VL, Komjathy SF, Collins ME, Sane DC, Scott HJ, Schlossberg ML, Herzog WR.  Regional and systemic platelet function is altered by myocardial ischemia-reperfusion. J Thromb Thrombolys 1995; 1:187-194.

14.       Serebruany VL, Herzog WR, Gurbel PA, Schlossberg ML, Scott HJ, Vogel RA.  NPC 15669, an anti-inflammatory leucine derivative reduces in vitro  platelet aggregability in both swine and human plasma.  J Thromb Thrombolys 1995;  1:171-178.

15.       Herzog WR, Gurbel PA, Vogel RA, Schlossberg ML, Scott HJ, Schneider AI, Serebruany VL.  Effects of NPC 15669 an anti-inflammatory leucine derivative on myocardial stunning and pre-conditioned infarction size in swine. J Thromb Thrombolys 1995;  1:163-170.

16.       Herzog WR, Schlossberg ML, MacMurdy KS, Edenbaum LR, Gerber MG, Vogel RA, Serebruany VL. Timing of magnesium therapy affects experimental infarct size. Circulation 1995; 92: 2622-2626.

17.       Serebruany VL, Herzog WR,  Atamas SP,  Gurbel PA, Paulsen G, Mortensen SA, Folkers K. Hemostatic Changes after dietary Coenzyme Q10 supplementation in swine.  J Cardiovasc Pharm 1996;  28: 175-181.

18.       Herzog WR, Serebruany VL. How magnesium therapy may influence clinical outcome in  acute myocardial infarction: review of potential mechanisms. Coron Artery Dis 1996; 7: 364-371.

19.       Serebruany VL, Herzog WR, Gurbel PA. Serial changes of natural antithrombotics during myocardial ischemia-reperfusion in swine. Effects of magnesium, diltiazem, and a novel Mac-1 inhibitor. Blood Coag Fibrinol 1996; 7: 632-640.

20.       Gurbel PA, Serebruany VL, Komjathy SF, Collins ME, Bittar GD, Schlossberg ML, Mergner W.  Pretreatment with an inhibitor of Mac-1 alters regional and systemic platelet function during ischemia - reperfusion in swine. Pharmacology 1996;  53: 79-86.

21.       Serebruany VL, Solomon SR, Edenbaum LR, Herzog, WR, Gurbel PA. Mac -1 inhibitor affects certain hemostatic  parameters during  myocardial  stunning in swine. Pharmacology 1996  53: 87-97.

22.       Serebruany VL, Schlossberg ML, Edenbaum LR, Herzog WR, Gurbel PA. Intracoronary magnesium and diltiazem affect to a similar extent certain hemostatic factors during acute myocardial infarction  in swine. Pharmacology 1996; 53: 224-233

23.       Serebruany VL, Schlossberg ML, Edenbaum LR, Herzog WR, Gurbel PA. Hemostatic changes after early versus late intracoronary magnesium during acute myocardial infarction in swine. J Cardiovasc Pharm 1996; 28: 817-823.

24.              Serebruany VL, Herzog WR, Edenbaum LR, Shustov AR, Gurbel PA. Changes in the haemostatic profile during magnesium deficiency in swine. Magnesium Res 1996; 9: 155-163.

25.       Serebruany VL, Ordonez JV, Herzog WR, Rohde M, Mortensen SA, Folkers K, Gurbel PA. Dietary coenzyme Q10 supplementation alters platelet size and inhibits human vitronectin (CD51/CD61) receptor expression. J Cardiovasc         Pharm 1997; 29: 16-22.

26.       Serebruany VL, Herzog WR, Gurbel PA. Serial changes of the  plasma prostanoids during  myocardial  ischemia - reperfusion  in  swine :  Effects of  magnesium,  diltiazem,  and a   novel  Mac-1 inhibitor. Prostagland Leukotr Essen Fatty         Acids 1997; 56: 135-142.

27.              Serebruany VL, Gurbel PA,  Ordonez JV, Herzog WR, Rohde M, Mortensen SA, Folkers K. Could coenzyme Q10 affect hemostasis by inhibiting platelet vitronectin (CD51/CD61) receptor ? Molec Aspects Med 1997; 18: S189-S194.

 

28.       Herzog WR, Vogel RA, Schlossberg ML, Edenbaum LR, Scott HJ, Serebruany VL. Short-term low dose intracoronary diltiazem administered at the onset of reperfusion reduces myocardial infarct size Intern J Cardiol 1997; 59: 21-27.

29.       Serebruany VL, Solomon SR, Herzog WR, Gurbel PA. Bolus magnesium infusion in humans is associated with predominantly unfavorable changes in platelet aggregation and certain hemostatic factors. Pharmacol Res 1997; 36: 17-22 .

30.       Serebruany  VL,  Schlossberg ML,  Edenbaum LR, Herzog WR, Gurbel PA. Effects of intracoronary diltiazem on certain hemostatic parameters during acute myocardial infarction in swine. Intern J Cardiol 1997; 61: 21-29.

31.       Gurbel PA, Serebruany VL. Myths and realities of P-selectin plasma levels in patients with acute myocardial infarction. Thromb Res 1997; 88: 343-344.

32.       Serebruany VL, Gurbel PA,  Shustov AR, Dalesandro M, Gumbs SI, Grabletz BS, Bahr RD, Ohman EM, Topol EJ. Depressed platelet status in a patient with hemorrhagic stroke following thrombolysis for acute myocardial infarction. Stroke 1998; 29: 235-238.

33.       Gurbel PA, Serebruany VL. Soluble Vascular Cell Adhesion Molecule and E-selectin in patients with acute myocardial infarction treated with thrombolytic agents. Am J Cardiol 1998; 81: 772-775.

34.       Serebruany VL,  Atar D, Dalesandro MR, O’Connor CM, Gurbel PA. Changes in hemostasis after parenteral magnesium  in myocardial ischemia - reperfusion : from animal studies  to clinical trials. Magnes Res 1998 11: 37-42.

35.       Serebruany VL, Bahr RD, O’Connor CM, Lowry DR, Gurbel PA, for the GUSTO-III Platelet Substudy. Antecedent aspirin therapy inhibits baseline platelet activity in patients  presenting with acute  myocardial infarction. Cardiology 1998; 90: 37-42.

36.       Serebruany VL , Solomon SR, Herzog WR, Gurbel PA.  Plasma fibronectin during  myocardial  ischemia - reperfusion.  Effects of  magnesium,  diltiazem,  and a   novel  Mac-1 inhibitor. Am J Hematol 1998; 57: 309-314.

37.       Serebruany VL, Solomon SR, Shustov AR, Herzog WH, Gurbel PA.                                 Survival in acute myocardial infarction induced by coronary artery ligation : Prognostic relevance of certain hemostatic factors during the occlusion phase. J Thromb  Thrombolys 1998; 5: 29-35.

38.       Serebruany VL, Ordonez JV, Yurovsky VV, Gurbel, PA. The crossreactivity of human vs. swine platelet surface antigens is similar for glycoproteins Ib and IIIa, but not for IIb/IIIa complex. J Thromb Thrombolys 1998; 5: 37-41.

39.       Gurbel PA, Serebruany VL, Shustov AR, Bahr RD, Carpo C, Ohman EM and  Topol EJ, for the GUSTO III Investigators. Effects of Reteplase and Alteplase on Platelet Aggregation and Major Receptor Expression During the First 24 Hours of  Acute Myocardial Infarction Treatment. The GUSTO III Platelet Study. J Amer Coll Cardiol 1998; 31: 1466-1473.

40.       Serebruany VL, Gurbel PA, Shustov AR, Ohman EM, Topol EJ. Heterogeneity of platelet aggregation and major surface receptor expression in patients presenting with acute myocardial infarction. Am Heart J 1998; 136: 398-405.

41.              Serebruany VL, Gurbel PA,  Murugesan SR, Lowry DR, Sturm E, Svetlov SI. Depressed plasma platelet-activating factor acetylhydrolase in patients presenting with acute myocardial infarction. Cardiology 1998; 90: 127-130.

42.              Serebruany VL , Schlossberg ML, Edenbaum LR,  Herzog WR, Gurbel PA. Serial changes of soluble endothelin-1 levels during  myocardial  ischemia-reperfusion.  Effects of  magnesium,  diltiazem,  and a novel  Mac-1 Inhibitor. Pharmacol Res 1998; 38: 165-172.

43.              Gurbel PA, Serebruany VL, Shustov AR, Dalesandro M, Gumbs SI, Grabletz BS, Bahr RD, Ohman EM, Topol EJ.  Increased  baseline platelet P-selectin, and PECAM-1 as predictors of unsuccessful thrombolysis  in patients with acute myocardial infarction. Coron Artery Dis 1998; 9: 451-456.

44.              Gurbel PA, Dalesandro MR, Serebruany VL. Effects of reteplase and alteplase on soluble PECAM-1 and P-selectin in patients with  acute myocardial infarction. Thromb Haemost  1998; 80: 725.

45.              Serebruany VL, Gurbel PA. Effect of thrombolytic therapy on the plasma concentration and platelet expression of the platelet/endothelial  cell adhesion molecule in patients with acute myocardial infarction. Arterioscl Thromb Vasc Biol 1999; 19: 153-158.

46.               Serebruany VL, Gurbel PA. The relations of major platelet receptor expression during myocardial infarction. Monitoring efficacy of GPIIb/IIIa inhibitors by measuring P - selectin ? Thromb Haemost 1999; 81 : 314-316.

47.              Serebruany VL, Gurbel PA. Assessment of platelet activity by measuring platelet-derived substances in plasma from patients with acute myocardial infarction: Surprising lessons from  the GUSTO-III  Platelet Study. Thromb Res 1999; 93: 149-150.

48.              Svetlov SI, Moscaleva ES, Pinelis VG, Daikhin YI, Serebruany VL. Decreased intraplatelet Ca2+ mobilization and ATP secretion in pediatric nephrotic syndrome. Pediatr Nephrol 1999; 13: 205-208.

49.              O’Connor CM, Gurbel PA, Serebruany VL. Usefulness of soluble and surface-bound P- selectin in detecting heightened platelet activity in patients with congestive heart  failure. Amer J  Cardiol 1999; 83: 1345-1349.

50.              Serebruany VL, Murugesan SR, Pothula A, Semaan H, Gurbel PA. Soluble Platelet / Endothelial Cellular Adhesion Molecule-1, but not P-Selectin, nor osteonectin identify acute myocardial infarction among patients with chest pain admitted to the Emergency Department. Cardiology 1999; 91: 50-55.

51.              Gurbel PA, Murugesan SR, Lowry DR, Serebruany VL. Plasma thromboxane  and prostacyclin are linearly related and increased in patients presenting with  acute myocardial  infarction. Prostagl Leukotr Essen Fatty Acids 1999; 61: 7-11.

52.              Nair GV, Gurbel PA, O’Connor CM, Gattis WM,     Murugesan SR, Serebruany VL. Depression, Coronary Events, Platelet Inhibition, and Serotonin Reuptake Inhibitors. Am J Cardiol 1999; 84: 321-323.

53.              Gurbel PA, O’Connor CM, Cummings CC, Serebruany VL. Clopidogrel : the future choice for preventing platelet activation during coronary stenting? Pharmacol Res 1999; 40: 107-111.

54.              Serebruany VL, Yurovsky VV, Gurbel PA. Effects of novel Mac-1 inhibitor NPC 15669 on hemostatic parameters during preconditioned myocardial infarction. Life Sci 1999; 65: 1503-1515.

55.              Murugesan SR, Gurbel PA, Serebruany VL. Storing paraformaldehyde   fixed whole blood patient samples after chronic platelet glycoprotein IIb/IIIa blockade : Core laboratory considerations. Thromb Res 1999; 95:201-203.

56.              Serebruany VL, Yurovsky VV, Gurbel PA. Mild myocardial stunning affects platelet aggregation and certain hemostatic factors in swine. Clin Appl Thromb Hemost 1999; 5: 236-242.

57.              Serebruany VL, Murugesan SR, Pothula A, Atar D, Lowry DR, O’Connor CM, Gurbel PA. Increased soluble Platelet/Endothelial Cellular Adhesion Molecule-1 and osteonectin levels in patients with severe congestive heart failure. Independence of disease etiology, and antecedent aspirin therapy. Eur J Heart Fail 1999; 1: 243-249.

58.              Serebruany VL, Kereiakes DJ, Dalesandro MR, Gurbel PA. Model of flow cytometer markedly affects platelet - bound P-selectin expression in patients with chest pain. Are we comparing apples with oranges ? Thromb Res 1999; 96:51-56.

59.              McKenzie ME, Gurbel PA, Levine DJ, Serebruany VL. Clinical utility of available methods determining platelet function. Cardiology 1999; 92: 240-247.

60.              Serebruany VL, Lowry DR, Fuzaylov SY, Levine DJ,  O’Connor CM, Gurbel PA. Moderate alcohol consumption is associated with  the decreased baseline platelet activity in patients presenting  with acute  myocardial  infarction. J Thromb Thrombolys 2000; 9: 229-234.

61.              McKenzie ME, Pothula A, Gurbel P, Fuzaylov SY, O’Connor CM, Gattis WA,    Serebruany VL. Failure of Thrombin Generation Markers to Triage Patients Presenting with Chest Pain. Cardiology 2000; 92: 53-58.

62.              Gurbel PA, Kereiakes DJ, Dalesandro MR, Bahr RD, O’Connor CM, Serebruany VL. The role of soluble and platelet-bound P-selectin in discriminating cardiac from non-cardiac chest pain at presentation in the emergency department. Am Heart J 2000; 139: 320-328.

63.              Serebruany VL, McKenzie ME, Levine DJ Gurbel PA. Monitoring Platelet Inhibition During Chronic Oral Platelet Glycoprotein IIb/IIIa Blockade: Are We Missing Something? Thromb Haemost 2000; 83: 356-357.

64.              Gurbel PA, DJ Kereiakes, Atar D, Serebruany VL. Baseline platelet aggregation and major receptor expression predict subsequent activity following thrombolysis for acute myocardial infarction. Scand Cardiovasc J 2000; 34: 53-58.

65.              Semaan HB, Gurbel PA, Anderson JL, Muhlestein JB, Carlquist JF, Horne BD,        Serebruany VL. VCAM-1 and E-selectin Indicate Endothelial Activation in Patients with Documented Coronary Artery Disease. Cardiology 2000; 93: 7-10.

66.              Nair GV, Gurbel PA, Fuzaylov SY, Davis CJ, Ohman EM, Bahr RD, Christensen RH, Serebruany VL. Combining necrosis and platelet markers for perfecting myocardial infarction rule out: How close are we? Cardiology 2000; 93: 50-55.

67.              Gurbel PA, McKenzie ME, Serebruany VL. Initial platelet activity may predict efficacy after chronic oral glycoprotein IIb/IIIa blockade: Should we consider uniform treatment regimens? Thromb Res 2000; 99: 105-107.

68.              Serebruany VL, Murugesan SR, D Atar, Jerome S, Semaan H, Gurbel PA. Effect of coronary thrombolysis on the plasma concentration of  osteonectin (SPARC, BM40)  in patients with  acute myocardial infarction. J Thromb Thrombolys 2000; 10: 197-202.

69.              Gurbel PA, Kereiakes DJ, Serebruany VL. Soluble P-selectin is not a surrogate marker for platelet P-selectin : Evidence from a multicenter chest pain study groop. J Thromb Thrombolys 2000; 10: 15-22.

70.              Pothula A, Serebruany VL Gurbel PA, McKenzie ME, Atar D. Pathophysiology and diagnostic utility of thrombin generation in patients with coronary artery disease. Europ J Pharm 2000; 402: 1-10.

71.              Fuzaylov SY, Serebruany VL. Amount of Paraformaldehyde for Sample Fixation Markedly Affects the Quality of Platelet Assessment by Flow Cytometry: Experience From Two Clinical Trials. Thromb Res 2000; 99: 643-644.

72.              O’Connor CM, Gurbel PA, Serebruany VL. Depression and ischemic heart disease. Am Heart J 2000; 140 (4 Pt. 2) 63-69.

73.              Semaan HB, Gurbel PA, Anderson JL, Muhlestein JB, Carlquist JF, Horne BD,        Serebruany VL. The effect of chronic azytromycin therapy on vascular adhesion molecules in patients with coronary artery disease. J Cardiovasc Pharm 2000; 36: 533-537.

74.              Davis CJ, Gurbel PA, Gattis WA, Fuzaylov SY, Nair GV, O’Connor CM, Serebruany VL. Hemostatic abnormalities in patients with congestive heart failure: Diagnostic significance and clinical challenge. Intern J Cardiol 2000; 75: 15-21.

75.              Serebruany, VL, Lowry DR. Take an Aspirin or Have a Drink : Antecedent Aspirin and Moderate Alcohol Consumption Similarly Affect Baseline Platelet Characteristics in Patients with Acute Myocardial Infarction. Thromb Haemost 2000; 84: 933-4.

76.               Gurbel PA, Serebruany VL. Oral Platelet IIb/IIIa Inhibitors: From Attractive Theory to Clinical Failures.  J Thromb Thrombolys 2000; 10: 217-220.

77.               Cummings CC, McKenzie ME, Horowitz ED, Oshrine BR, Callahan KP, Gurbel PA, Serebruany VL. Platelet Function and Total Length of Intracoronary Stents: Is There a Correlation? Thromb Res 2001; 105-107.

78.              Bell CR, Horowitz ED, Oshrine BR, Serebruany VL. Profound Inhibition of GPIb, GPIIb/IIIa, PECAM-1, CD63, and CD107 in a Chronic Drug Addict: Selecting Controls for Platelet Flow Cytometry in the Inner City Hospital. Thromb Res 2001; 101: 217-218.

79.              Gurbel PA, Dalesandro MR, O’Connor CM, Serebruany VL. Relation of soluble and platelet p-selectin to early outcomes in patients with  acute myocardial infarction after thrombolytic therapy. Am J Cardiol 2001; 87: 774-777.

80.              Serebruany VL, Davis CJ, Meister AF, Atar D, Whellan DJ, O’Connor CM. Biomarkers and exercise training: A possible missing link between physical activity and mortality benefit in patients with heart failure. HeartDrug 2001; 1: 110-24.

81.              Serebruany VL, Alford AB, Meister AF, Fuzaylov SY, Gattis WA, Gurbel PA, O’Connor CM. Clinical Utility of The Platelet Function Analyzer (PFA-100 â) for the AssEssment  of the  Platelet  Status  in  Patients with  COngestive HearT Failure (EPCOT Trial) Thromb Res 2001; 101: 427-433.

82.              Nair GV, Davis CJ, McKenzie ME, Lowry DR, Serebruany VL. Aspirin in Patients with Coronary Artery Disease: It is Simply Irresistable? J Thromb Thrombolys 2001; 11: 117-26.

83.              Serebruany VL, Levine DJ, Nair GV, Meister AF, Gurbel PA.Usefulness of combining necrosis and platelet markers in triaging patients presenting with chest pain to the emergency department. J Thromb Thrombolys 2001; 11: 155-162.

84.              Serebruany VL, Malinin AI, Bell CR, Gurbel PA. Heparin prevents Xylum Clot Signature Analyser to detect platelet inhibition with clopidogrel during coronary stenting. Thromb Res 2001; 102: 95-97.

85.              Serebruany VL, Gurbel PA, O’Connor CM. Platelet Inhibition by Sertraline and N-Desmethylsertraline : A Possible Missing Link Between Depression, Coronary Events, and Mortality Benefits of Selective Serotonin Reuptake Inhibitors. Pharm Res 2001; 43: 453-62.

86.              Serebruany VL, O’Connor CM, Gurbel PA. Effect of selective serotonin reuptake inhibitors on platelets in patients with coronary artery disease. Amer J Cardiol 2001; 87: 1398-1400.

87.              Callahan KP,  Malinin AI,  Gurbel PA,  Alexander JH,  Granger CB, Serebruany VL. Platelet Function and Fibrinolytic Agents: Two Sides of a Coin? Cardiology 2001; 95: 55-60.

88.              Serebruany VL, Cummings CC, Malinin AI, Steinhubl SR, Gurbel PA. Uniform platelet activation exists before coronary stent implantation despite aspirin therapy.

            Am Heart J, 2001; 142: 611-616.

89.              Serebruany VL, Steinhubl SR, Malinin AI, Kallahan KP, Gurbel PA. Statins do not affect platelet inhibition with clopidogrel during coronary stenting. Atherosclerosis, 2001; 239: 259-261.

90.              Callahan PA, Malinin AI, Atar D, Serebruany VL. Platelet Activation as a Universal Trigger in the Pathogenesis of Acute Coronary Events After Cocaine Abuse. Swiss Med Wkly, 2001; 131: 487-9.

91.              Malinin AI, Callahan KP, Serebruany VL. Paradoxical Activation of Major Platelet Receptors in the Methadone-Maintained Patients After Single Pill of Aspirin. Thromb Res 2001; 104: 297-9.

92.                  Callllahan KP, Malinin AI,  Gurbel PA,  Alexander JH,  Granger CB, Atar D, Serebruany VL.  Platelets and Thrombolysis: Cooperation or Contrariety? Heart Drug  2001; 1:281-290.

93.              Gurbel PA, Serebruany VL. Adhesion molecules, platelet activation, and cardiovascular risk. Editorial. Am Heart J 2002; 143-196-8.

94.              Serebruany VL, McKenzie ME, Meister AF, Fuzaylov SY, Gurbel PA, Atar D, Gattis WA, O'Connor CM: Failure of Platelet Parameters and Biomarkers to Correlate Platelet Function to Severity and Etiology of Heart Failure in Patients Enrolled in the EPCOT Trial. With special reference to theHemodyne Hemostatic Analyzer. Pathophys Hemost Thromb 2002;32:8-15.

95.              Malinin AI, Atar D, Serebruany VL. Selective Serotonin Reuptake Inhibitors: Future Treatment of Vascular Disease? HeartDrug 2002; 1:332-340.

96.              McKenzie ME, Bell CR, Horowitz ED, Oshrine BR, Atar D, Serebruany VL. Effects of in vitro exposure of alcohol on surface receptor expression of human platelets. Clyn Physiol Funct Imaging 2002; 22: 153-156.

97.              Gurbel PA, Malinin AI, Callahan KP, Serebruany VL, O’Connor CM. Effect of Loading With Clopidogrel at the Time of Coronary Stenting on Platelet Aggregation and Clycoprotein IIb/IIIa Expression and Platelet-Leucocyte Aggregate Formation. Am J Cardiol 2002; 90:14-17.

98.              Gurbel PA, Gatis WA, Fuzailov Syu, Gaulden L, Hasselblad V, Serebruany VL,  O’Connor CM. Evaluation of platelets in heart failure: is platelet activity related to etiology, class or clinical outcomes? Am Heart J 2002; 143: 1068-1075.

99.              Malinin AI, Eisert RM, Atar D, Barkagan ZS and Serebruany VL. Aggrenox® (Extended Release Dipyridamole And Low Dose Aspirin in Combination): Protecting Platelets From Excessive Activation in Patients With Vascular Events. HeartDrug 2002; 2: 93-104.

100.          Bahr RD, Gurbel PA, Malinin AI, Wentz C, Christenson RH, Roe MT, Gibler WB, Kitt MM, Ohman EM, Serebruany VL for the EARLY Trial Investigators. Relation of Platelet Activation and Myocardial Ischemia Biomarkers Dependent to Type of Chest Pain (Abrupt Onset – vs – Intermittent) in Patients with Angina Pectoris or Non -Q Wave Acute Myocardial Infarction. Am J Cardiol 2002; 90:310-312.

101.          Gurbel PA, Malinin AI, Callahan KP, Serebruany VL, O’Connor CM. Effect of loading with clopidogrel at the time of coronary stenting on platelet aggregation, glycoprotein Iib/IIIa expression, and platelet-leukocyte aggregate formation. Am J Cardiol 2002; 90: 312-315

102.          Serebruany VL, McKenzie ME, Meister AF, Fuzaylov SYu, Gurbel PA, Gattis WA,           O’Connor CM. Whole Blood Impedance Aggregometry for the AssEssment of the    Platelet  Function  in  Patients with  COngestive HearT Failure (EPCOT Trial). Europ J Heart Fail 2002;4:461-466.

103.          Gurbel PA, Kallahan KP, Malinin AI, Serebruany VL, Gillis J. Could stent design affect platelet activation? Results of the Platelet Activation in Stenting (PAST) trial. J Invas Cardiol 2002; 14: 584-9.

104.          Sane DC, McKee, SA, Malinin AI, Serebruany VL. Frequency of aspirin resistance in patients with congestive heart failure treated with antecedent aspirin. Am J Cardiol 2002; 90; 893-894.

105.          McKenzie ME, Bell CR, Horowitz ED, Oshrine BR, Malinin AI, Atar D, Serebruany VL. Aspirin inhibits surface GPIIb/IIIa, P-selectin, CD63, and CD107a receptor expression on human platelets. Blood Coag Fibrinol 2003; 14: 1-5.

106.          Gurbel PA, Cummings CC, Bell CR, Alford AB, Meister AF, Serebruany VL. Onset and Extent of Platelet Inhibition by Clopidogrel Loading in Patients Undergoing Elective Coronary Stenting – The PRONTO (Plavix Reduction of New Thrombus Occurrence) Trial. Am Heart J 2003; 145: 239-247.

107.          Malinin AI, Atar D, Callahan KP, McKenzie ME, Serebruany VL. Effects of a single dose aspirin on platelets in humans with multiple risk factors for coronary artery disease. Europ J Pharm 2003; 462: 139-143.

108.             Serebruany VL. Antipletelet properties of sertraline and survival benefits in patients with depression after acute coronary events. Acute Coron Syndr 2003; 5: 76-80.

109.             Serebruany VL, Malinin AI, Callahan KP, Binbreck AS, van de Werf F, Alexander JH, Granger CB, Gurbel PA. Effect of Tenecteplase versus Alteplase on Platelets in Patients During the First Three Hours of Treatment of Acute Myocardial infarction (The ASSENT-2 Platelet Substudy). Am Heart J 2003; 245: 636-642.

110.             Malinin AI, O’Connor CM, Dzhanashvili AI, Sane DC, Serebruany VL. Platelet Activation in Patients with Congestive Heart Failure: Do We Have Enough Evidence to Consider Clopidogrel? Am Heart J 2003;145:397-403.

111.             Serebruany VL, Malinin AI, Sane DC.  “Rapid platelet inhibition after a single pill Aggrenox®: Challenging a conventional full-dose aspirin antiplatelet  advantage?” Am J Hematol 2003;72:280-281.

112.             Serebruany V.L., Steinhubl SR, Hennekens CH. Are antiplatelet effects of clopidogrel inhibited by atorvastatin? A research question formulated but not yet adequately tested (Editorial). Circulation 2003;107:1568-1569.

113.             Serebruany VL, Glassman AH, Malinin AI, Atar D, Sane DC, Oshrine BR, Ferguson JJ, O’Connor CM. Selective serotonin reuptake inhibitors yield additional antiplatelet protection in patients with congestive heart failure treated with antecedent aspirin. Europ J Heart Fail 2003: 5: 517-521.

114.          Serebruany VL, Malinin AI, O’Connor CM, Gurbel PA. Effects of roxifiban on platelet   aggregation and major receptor expression in patients with coronary artery  disease. For the Roxifiban Oral Compound Kynetics Evaluation Trial-I (The ROCKET-I Platelet Substudy). Amer Heart J 2003; 146: 91-98.

115.          Serebruany VL, Glassman AH, Malinin AI, Nemeroff CH, Musselman DT,  Krishnan RR, van Zyl LT, Finkel MS Harrison W, Califf RM, O’Connor CM for the SADHART Study Group. Platelet/Endothelial Biomarkers in Patients Treated with Selective Serotonin Reuptake Inhibitor for Depression after Acute Coronary Events: The Sertraline AntiDepressant Heart Attack Randomized Trial (SADHART) Platelet Substudy. Circulation, 2003; 108:939-944.

116.          Gurbel PA, Galbut B, Bliden KP, Bahr RD, Roe MT, Serebruany VL, Gibler WB, Christenson RH, Ohman EM. Effect of Eptifibatide for acute coronary syndromes: Rapid versus late administration-therapeutic yield on Patients (The EARLY Platelet Substudy). J Thromb Thrombolys 2002; 14: 213-219.

117.          Serebruany VL, Glassman AH, Malinin AI, Sane DC, Finkel MS, Krishnan RR, Lekht V, O’Connor CM, Platelet/Endothelial activation in depressed patients after acute myocardial infarction and unstable angina: Evidence from clinical trials. Blood Coag Fibrin 2003; 14: 1-5

118.          Saw J, Steinhubl S, Berger P, Kereiakes D, Serebruany V, Brennan D, Topol E. Lack of clinical evidence of clopidogrel – atorvastatin interaction in a randomized, controlled clinical trial. Circulation 2003; 108: 921-924.

119.          Serebruany VL, Malinin AI, Jerome SD, Lowry DR, Morgan AW, Sane DC, Tanguay J-F, Steinhubl SR, O’Connor CM. Effect of clopidogrel and aspirin combination versus aspirin alone on platelet aggregation and major receptor expression in patients with heart failure: The Plavix Use for Treatment Of Congestive Heart Failure (PLUTO-CHF) trial. Am Heart J 2003; 146:713-720.

120.          Serebruany VL, Malinin AI, Sane DC. Risk of Bleeding Complications With Antiplatelet Agents: A Meta-Analysis of 338,191 Patients Enrolled in 50 Randomized Controlled Trials. Am J Hemat 2004; 75: 40-47.

121.          Joynt KE,  Gattis WA, Hasselblad V,  Fuzaylov SA, Serebruany VL, Gurbel PA,  Gaulden LH,  Felker GM, Whellan DJ, O’Connor CM. Effect of angiotensin receptor inhibitors, beta blockers, statins, and aspirin on C-reactive protein levels in outpatients with heart failure. Am J Cardiol 2004; 93: 783-785.

122.          Serebruany VL, Malinin AI, Lowry DR, Sane DC, Webb RL, Gottlieb SO, Hennekens CH. Platelet Inhibition by Valsartan and Valeryl 4-hydroxy Valsartan: A Possible Missing Link to Explain Benefits of Angiotensin II Receptor Blockers in Patients After Acute Vascular Events. J Cardiovasc Pharm 2004; 43: 677-684.

123.          Malinin A, Spergling M, Muhlestein B, Michelson A, Steinhubl S, Serebruany V. Assessing Aspirin Responsiveness in Subjects with Multiple Risk Factors for Vascular Disease with the Rapid Platelet Function Analyzer  Blood Coag Fibrinol 2004; 15: 1-7.

124.          Malinin AI, Oshrine BR, Serebruany VL. Should We Consider Selective Serotonin Reuptake Inhibitors for Treating Wound Healing? Medical Hypothesis 2004; 63: 103-109.

125.          Serebruany VL,  Oshrine BR, Malinin AI, Sane DC, Takserman A, Atar D, Hennekens CH. Lack of the uniformed platelet activation in patients after ischemic stroke: Does aspirin matters? Thromb Research 2004; 113: 197-204.

126.          Serebruany VL, Hanley DF,  Atar D, Ferguson JJ. Non - compliance in antiplatelet trials: The AGATE trial perspective. Stroke 2004; 35: 143.

127.          Serebruany VL, Malinin AI, Sane DC, Takserman A, Atar D, and Hennekens CH. Magnitude and time course of platelet inhibition with Aggrenox and aspirin in patients after ischemic stroke. The AGgrenox versus Aspirin Therapy Evaluation (AGATE) Trial. Europ J Pharm 2004; 499:315-324.

 

B. Accepted:

1.                  Serebruany VL, Suckow RF, Cooper TB, Glassman AH, Malinin AI, Krishnan RR, Lekht V, Harrison W, Clary CM, O’Connor CM for the SADHART trial. Release of Platelet/Endothelial Biomarkers Negatively Correlates with the Plasma Levels of Sertraline and N-Desmethylsertraline in Depressed Patients After Acute Coronary Syndromes Treated with Selective Serotonin Reuptake Inhibitor. Am J Psych

2.                  Serebruany VL, Midei MG, Malinin AI, Oshrine BR, Lowry DR, Sane D, Tanguay JF, Steinhubl SR, Berger PB, O'Connor CM, Hennekens CH.  Absence of Interaction Between Atorvastatin and Clopidogrel in Prospective Data:  The Interaction of Atorvastatin and Clopidogrel (INTERACTION Study). Arch Int Med

3.                  Serebruany VL. Reteplase plus abciximab improves non-fatal outcomes, but not overall survival in people with diabetes and acute  ST-elevation myocardial infarction (Commentrary). Evidence Based Healthcare.

4.                  Serebruany VL, Steinhubl SR, Berger PB, Bhatt DL, Michelson AD, Topol EJ. Variability in Platelet Responsiveness to Clopidogrel Among 544 Individuals. JACC

 

C. Submitted:

 

1.                  Malinin AI, Oshrine BR, Sane DC, O’Connor CM, Serebruany VL. Does Heart Failure Etiology, NYHA Class, or Ejection Fraction Affect the Ability of Clopidogrel to Inhibit Heightened Platelet Activity? Blood Coag Fibrinol

2.                  Serebruany VL, Oshrine BR, Malinin AI,  Michelson AD,  Jerguson JJ. Noncompliance in Clinical Trials (Editorial). Am Heart J

3.               Serebruany VL, Malinin AI, Berger PB, Steinhubl SR, Baggish JS, Bhatt DL, Topol EJ. The Risk of Bleeding Complications After Different Doses of Aspirin: A post-hoc Analysis of 192,036 Patients Enrolled in 31 Randomized Controlled Trials. Ann J Med

4.               Kotzailias N,  Dukic A,  Serebruany VL,  Jilma B. Safety and Efficacy of Co-administration of the selective Serotonin Reuptake Inhibitor Paroxetine and Aspirin in Male Smokers -a prospective randomized placebo controlled study. J Thromb Haemost

5.               Oshrine BR, Malinin AI,  Pokov AN,  Dragan A, Serebruany VL. Changes of pH are critical for accurate fluorometric measurements of dipyridamole levels in biological fluids. Clin Pharmacokin

6.               Serebruany VL, Pokov AN, Malinin AI, Sane DC, Tanguay J-F, Bhatt D, and Hennekens CH. Effect of valsartan on platelets in patients with mild to moderate hypertension: The Valsartan Inhibits Platelets (VIP) Trial Circulation

Abstracts :

1.         Serebruany VL.  Immunological   profile  in   children with acute leukemia, undergoing BCG-vaccine treatment. Medical student’s conference. Erevan, (Armenia) 1982; 178-179.

2.         Manin VM, Rumyantzev AG, Serebruany VL. Rehabilitation programs for children with acute lymphoblastic leukemia. USSR Hematology Symposium. Orel, 1982; 108-109.

3.         Axelrod VG, Serebruany VL. Efficiency of “Pulmarka” ® (Drager AG, Germany) in the treatment of respiratory distress syndrome in premature  newborns. Russian Perinatology  Symposium. Moscow, 1983; 7-8.

4.         Axelrod VG, Serebruany VL. Transcutaneous PaO2 detection in the newborns.Medical Research Fellow’s Conference. Moscow, 1984; 3-4.

5.         Vichireva ZN, Serebruany VL. Peroxydation of lipids during newborn sepsis. USSR Hematology Symposium. Orel, 1984, 38-39.

6.         Gavrushev VV, Axelrod VG, Serebruany VL. Treatment of hypoxemia in the newborns with the continuos negative air pressure. XII Pediatric Congress of Estonia. Tallinn, 1985; 1 : 105-106.

7.         Stuklov VI, Medvedev MV, Serebruany VL. Role of echography in the detection of congenital urinary tract malformations in fetus. III USSR Congress on Obstetrics & Gynecology. Alma-Ata, Kazachstan 1985; 201-202.

8.         Serebruany VL, Barkagan LZ.  Hemostasis in children with the nephrotic syndrome. Inter J Pediatric Nephrol, 1987; 8 : 112.

9.         Barkagan LZ, Serebruany VL, Anmut NY. Platelet aggregation and von Willebrand factor in children with immune nephropathies. Ibid, p.125.

10.       Serebruany VL, Ignatova MS, Degtyareva EM. Thrombotic complications in children with minimal change nephrotic syndrome, USSR Conference on Thrombosis & Hemostasis, Moscow, 1987; 83-84.

11.       Svetlov SI, Serebruany VL. Plasma platele activating factor levels in children undergone chronic hemodialysis. Ibid, 98-99.

12.       Serebruany VL, Medvedev MV, Davidov AI.  Antenatal ultrasound diagnosis of kidneys and urinary tract malformations. Union Symposium on Perinatology. Moscow, 1987, 105-107.

13.       Medvedev MV, Serebruany VL, Axelrod VG.  Estimation of heart ventricles function in fetus and in the newborn, using echocardiography. Ibid, 108-109.

14.       Veltischev YE, Serebruany VL, Svetlov SI, Moskaleva ES. Platelet function in children with the chronic renal  failure, estimated by platelet aggregation in response to different inductors. Vth European Symposium on Pediatric Nephrology . Warsaw (Poland) 1988; 15.

15.       Kopileva OD, Degtyareva EM, Serebruany VL. Analysis of clinical outcomes in children with Henoch - Schönlein nephritis. VII Russian Nephrology Congress. Novosibirsk, 1988; 34-35.

16.       Serebruany VL. Hemostatic abnormalities due to heparin treatment  in children with nephrotic syndrome. Ibid, 66-67.

17.       Veltischev YE, Svetlov SI, Serebruany VL. Platelet response to the platelet-activating factor during the nephrotic syndrome in children, XXI European Congress of Pediatric Nephrology, Pediatr Nephrol 1989; 3 : 147.

18.       Serebruany VL, Degtyareva EM. Heparin treatment in patients with mesangiocapillary glomerulonephritis. Russian Hematology Symposium.1989; 101-104.

19.       Veltischev YE, Svetlov SI, Serebruany VL, Pinelis VG.  Platelet-activating factor, thromboxane B2 and platelet aggregation in children with the nephrotic  syndrome. VIII World Congress on Pediatric Nephrology. Pediatr Nephrol 1989; 4  : C171.

20.       Serebruany VL, Kubatiev AA. Plasma prostacyclin level in children with the nephrotic syndrome. Ibid,  C170.

21.       Serebruany VL, Kubatiev AA, Smirnov IE. Changes of plasma prostacycline  in children with the nephrotic syndrome during the isolated prednisolone therapy. III International Congress on Prostaglandins. Washington, D.C., 1991; # 372

22.       McLean RH, Serebruany VL, Delaney N, Lin X-Y, Wang S-R, Bias W H.                                               Rare slow C4B allele in Taiwanese lupus patients. XI International Histocompatibility Workshop. Yokohama, (Japan) 1991.

23.       Oei AS, Herzog WR, Bartlett ST, Evans D, Serebruany VL. Platelet aggregation in patients with renal  transplantation. International research conference, UMAB, Baltimore. 1993; 38.

24.       Khan ZS, Serebruany VL, Schlossberg ML, Herzog WR. Effect of coenzyme Q10 on  myocardial stunning in swine. Ibid; 24.

25.       Herzog WR, Atar D, Mortensen SA, Schlossberg ML, Serebruany VL. Effect of Coenzyme  Q10 supplementation  on platelet aggregability in swine. X European Symposium “Q10 in clinical practice”. Stockholm, 1993.

26.       Herzog WR, Rinder MR, Atar D, Serebruany VL. Platelet aggregability decreases after magnesium  infusion in swine with initial normal serum magnesium  level. American Heart Association,  Anaheim, 1993.

27.       Gurbel PA, Komjathy SF, Collins ME, Scott HJ, Schlossberg ML, Serebruany VL, Herzog WR.  Both coronary and systemic platelet aggregation are enhanced following reperfusion after brief ischemia. Eur Heart J 1994; 15:106.

28.       Gurbel PA, Serebruany VL, Komjathy SF, Collins ME, Schlossberg ML, Herzog WR.  The effect of myocardial ischemia/reperfusion on regional and systemic platelet function.  Clin Res 1994; 42:163A.

29.       Gurbel PA, Komjathy SF, Collins ME, Schlossberg ML, Serebruany VL, Herzog WR. Intravenous administration of NPC15669, a leumedin, markedly reduces myocardial stunning.  Clin Res 1994; 42:163A.

30.       Herzog WR, Atar D, Rinder MR, Gurbel PA, Serebruany VL. Magnesium infusion decreases platelet aggregability in swine.  J Am Coll Cardiol 1994;       23:31A.

31.       Schlossberg ML, Herzog WR, Rinder MR, Serebruany VL, Gurbel PA, Schneider AI, Edgeworth N, Pou S, Rosen GM.  Intracoronary nitroprusside         delivery ameliorates myocardial stunning with systemic effects.  Clin Res 1994; 42:163.

32.       Schlossberg ML, Herzog WR, Rinder MR, Serebruany VL, Gurbel PA.              Intracoronary Nitroprusside delivery ameliorates myocardial stunning with minimal systemic effects. American Federation for Clinical  Research Meeting, Baltimore. 1994. 715-3:87A.

33.              Herzog WR, Mortensen SA, Serebruany VL.  Dose dependent effects of Coenzyme Q10 on platelet aggregation in swine. Ibid, 94A.

34.       Gurbel PA, Serebruany VL, Komjathy SF, Collins ME, Scott H, Schlossberg ML, Herzog WR.  Intravenous NPA 15669, a leumedin, selectively inhibits regional platelet hyperaggregability that develops during myocardial ischemia - reperfusion. Circulation 1994;  90:I-373.

35.       Herzog WR, Gurbel PA, Cowfer JP, Mann DJ, Serebruany VL. Intracoronary MgS04 during reperfusion limits infarct size in a swine model.  Magnes Res 1994; 7:67.

36.       Serebruany VL, Schlossberg ML, Gurbel PA, Vogel RA, Herzog WR. Effect of NPC 15669 on Myocardial Stunning and Infarction Size in Swine.  J Am Coll Cardiol 1995; 931-110:116A.

37.       Serebruany VL, Solomon SR, Gurbel PA, Herzog WR. Mg-deficiency in swine  is associated with hemostatic disorder. Eur Heart J 1995; 16:137.

38.       Mortensen SA, Cestatello JA, Serebruany VL, Herzog WR, Rohde M, Lingle DM, Whitman GJR. Coenzyme Q10 therapy: A cardiometabolic approach which favorably modulates ischemia and thus may prevent failure. International Meeting on Heart Failure. Amsterdam, 1995.

39.       Serebruany VL, Herzog WR, Gurbel PA. Bolus magnesium infusion unfavorably affects platelet aggregability and certain hemostatic factors in human volunteers. Eur Heart J 1996; 17: 77.

40.       Serebruany VL, Shustov AR, Gurbel PA, Herzog WR. Effects of Mac-1 inhibitor on hemostasis during myocardial stunning in swine. J Am Coll Cardiol 1996; 27: 2A.

41.       Serebruany VL, Herzog WR, Gurbel PA. Mild myocardial stunning affects platelet aggregation and hemostasis in swine. FASEB J. 1996; 10:A34.

42.       Serebruany VL, Herzog WR, Gurbel PA. Bolus magnesium infusion in humans is associated with predominantly unfavorable changes in  platelet aggregation and certain hemostatic factors. J Am Coll Cardiol 1997; 29: 134A.

43.       Serebruany VL, Rohde M, Mortensen SA, Folkers K, Morgan AW, Gurbel PA. Dietary  Coenzyme Q10 Supplementation inhibits human platelet vitronectin (CD51/CD61) receptor expression. Proc Soc Exper Biol Med 1997; 215: 109.

44.       Gurbel PA, Serebruany VL, Bahr RD, Shustov AR, Ohman EM. Effects of alteplase and reteplase on platelet aggregation and           major surface antigen receptor expression during the first 24 hours in patients with acute myocardial infarction. The GUSTO-III platelet study. Circulation 1997; 96: I 261.

45.       Serebruany VL, Bahr RD, Shustov AR, Carpo C, Gurbel PA. Marked heterogeneity of platelet aggregation and surface receptor expression in patients presenting with acute  myocardial infarction. Circulation 1997; 96: I 262.

46.       Gurbel PA, Serebruany VL, Dalesandro MR, O’Connor CM. Course of platelet and soluble P-Selectin  in patients with  acute myocardial infarction after thrombolytic therapy: New marker of successful reperfusion ? The XIIIth       World Congress of Cardiology. Rio de Janeiro, (Brazil), 1998.

47.       Serebruany, VL, O’Connor CM, Gurbel PA. Effect of coronary         thrombolysis on the platelet expression and plasma concentration of the Platelet/Endothelial Cell Adhesion Molecule - 1 (PECAM-1, CD31) in patients with acute myocardial infarction. Ibid, 1998.

48.      Serebruany VL, Murugesan SR, Pothula A, Semaan H, Jerome S, Gurbel    PA. Effect of  coronary thrombolysis on the plasma concentration of  osteonectin (SPARC, BM40)  in patients with  acute myocardial infarction. J Amer Coll Cardiol 1999; 33: 382A.

49.              O’Connor CM, Gurbel PA, Serebruany VL. Soluble and surface-bound P-selectin        reveal heightened platelet activity in patients with decompensated heart failure : Is aspirin Therapy Enough? J Amer Coll Cardiol 1999; 33: 206A.

50.              Serebruany VL, Murugesan SR, Gurbel PA. Storing paraformaldehyde fixed whole blood patient samples after chronic platelet glycoprotein IIb/IIIa blockade : Core laboratory considerations. XVII Congress of the International Society on Thrombosis and Haemostasis, Washington, D.C. Thromb Haemost 1999; 82: Suppl: 637.

51.              Gurbel PA, Kereiakes DJ, Dalesandro MR, Serebruany VL. The role of platelet and soluble P-selectin in discriminating cardiac from non-cardiac chest pain at presentation to the Emergency Department. Idid; 447-448.

52.              Serebruany VL, Kereiakes DJ, Atar D, Gurbel PA. Baseline platelet aggregation and major receptor expression predict subsequent  activity following thrombolysis for acute myocardial infarction. Ibid; 455-456.

53.              Gurbel PA, Kereiakes DJ, Atar D, Serebruany VL. Soluble and platelet P-selectin in patients with chest pain : Evidence for endothelial origin. Ibid; 628.

54.              Serebruany VL, Murugesan SR, Atar D, O’Connor CM, Gattis WA, Gurbel PA. Increased soluble PECAM-1 and osteonectin levels in patients with severe congestive heart failure. Idid; 657.

55.              Serebruany VL, Murugesan SR, Kereiakes DJ, Dalesandro MR, Gurbel PA. Flow cytometer model markedly affects the measurements of platelet-bound P-selectin in patients presented with chest pain. Ibid; 637.

56.              Serebruany VL, Murugesan SR, Kereiakes DJ, Dalesandro MR, Gurbel PA. Flow cytometer model markedly affects the measurements of platelet P-selectin in patients  with chest pain. XXI Congress of the European Society of Cardiology. Barselona, Spain. Europ Hear J 1999; 20:190.

57.              Gurbel PA, O’Connor CM, Gattis WA, Serebruany VL. Soluble and surface-bound P-selectin reveal heightened platelet activity in patients with decompensated heart failure : Is aspirin therapy enough? Ibid: 198.

58.              Serebruany VL,  Kereiakes DJ, Atar D, Gurbel PA. Baseline platelet           aggregation and major receptor expression predict subsequent activity following thrombolysis for acute myocardial infarction. Ibid: 120.

59.              Gurbel PA,  Kereiakes DJ,  Atar D, Serebruany VL. Soluble P-selectin in patients presenting with chest pain : Evidence for endothelial origin. Ibid:420.

60.              Serebruany VL, Murugesan SR, Atar D, O’Connor CM, Gattis WA, Gurbel PA. Increased soluble PECAM-1 and osteonectin levels in patients with severe congestive heart failure. Idid; 199.

61.              Serebruany VL, Gurbel PA, O’Connor CM. Platelet Inhibition by Sertraline and N-Desmethylsertraline: A Possible Missing Link to Explain Benefits of Selective Serotonin Reuptake Inhibitors in Depressed Patients after Acute Coronary Events. J Am Coll Cardiol 2000; 35: (Suppl.A 282).

62.              Serebruany VL, Gurbel PA, O’Connor CM. Platelet Inhibition by Sertraline and N-Desmethylsertraline: A Possible Missing Link to Explain Benefits of Selective Serotonin Reuptake Inhibitors in Depressed Patients after Acute Coronary Events. Europ Heart J 2000; 21 Suppl.: 179.

63.              Serebruany VL, Fuzaylov SY, Gattis WA, Gurbel PA,  O’Connor CM. Utility of cartridge-based analyzers in the Evaluation of Platelet function in patients with Congestive heart failure  Trial (EPCOT). Ibid; p.297.

64.              Semaan HB, Gurbel PA,  Muhlestein JB, Carlquist JF, Horne BD, Anderson JL,  Serebruany VL. The effect of chronic azithromycin therapy on soluble endothelial derived adhesion molecules in patients with coronary artery disease. AHA-2000.

65.              Gurbel PA, Cummings CC, Alford AB, Meister AF, Serebruany VL. Onset and Extent of Platelet Inhibition by Loading Dose Clopidogrel in Patients Undergoing Elective Coronary Stenting – The PRONTO (Plavix for Reduction of New Thrombus Occurrence) Trial. JACC; 2001 37: 32.

66.              Serebruany VL, O’Connor CM,  Gurbel PA. Selective Serotonin Reuptake Inhibitors Affect Platelets in Patients Undergoing Coronary Stenting. JACC; 2001 37 : 299-300.

67.              McKenzie ME, Bell CR, Horowitz ED, Oshrine BR, Serebruany VL.Aspirin Inhibits GPIIb/IIIa, P-selectin, CD63, and CD107a Surface Receptor Expression on Human Platelets. JACC; 2001 37: 224

68.              Serebruany VL, O’Connor CM,  Gurbel PA. Selective Serotonin Reuptake Inhibitors Affect Platelets in Patients Undergoing Coronary Stenting. Thromb Haemost; 2001 86 : 195.

69.              Malinin AI, McKenzie ME, Horowitz ED, Oshrine BR, Serebruany VL.Aspirin Inhibits GPIIb/IIIa, P-selectin, CD63, and CD107a Surface Receptor Expression on Human Platelets. Thromb Haemost; 2001 86: 208.

70.              Serebruany VL, Malinin AI, Bell CR, Gurbel PA. Heparin prevents Xylum Clot Signature Analyser to detect platelet inhibition with clopidogrel during coronary stenting. Thromb Haemost; 86: 223.

71.              Gurbel PA, Cummings CC, Alford AB, Meister AF, Serebruany VL. Onset and Extent of Platelet Inhibition by Loading Dose Clopidogrel in Patients Undergoing Elective Coronary Stenting – The PRONTO (Plavix for Reduction of New Thrombus Occurrence) Trial. Europ Heart J; 2001; 194.

72.              Serebruany VL, Malinin AI, Callahan KP, Binbreck AS, van de Werf F, Alexander JH, Granger CB, Gurbel PA. Effect of Tenecteplase versus Alteplase on Platelets in Patients During the First Three Hours of Treatment of Acute Myocardial infarction (The  ASSENT-2 Platelet Substudy). Circulation 2001; 104: 539

73.              Gurbel PA, Malinin AI, Callahan KP, Serebruany VL. Loading With 300mg Clopidogrel at the Time of Coronary Intervention Results in Decreased  Platelet Aggregation, GPIIb/IIIa Expression and Activation of Platelet-Leukocyte Aggregates. Circulation 2001; 104:707

74.              Serebruany VL, Glassman AH, Malinin AI, Krishnan RR, Finkel MM, Nemeroff C, Gurbel PA, Clary C, Harrison W, O'Connor CM. Effects of Zoloft® on Platelet/Endothelial Biomarkers in Depressed Patients After Acute Coronary Events: Sertraline Anti-Depressant Heart Attack Randomized Trial (SADHART Platelet Substudy). JACC 2002; 39 (supplement A): 286A, and WCC-2002, Sydney, 2002, and European Society of Cardiology Meeting (Berlin, 2002).

75.              Gurbel PA, Malinin AI, Callahan KP, Buczkowski MJ, Serebruany VL. How Rapidly and Durably Are Platelets Inhibited by a 300 mg Clopidogrel Loading Dose Given at the Time of Intervention Compared to Loading Before Intervention? JACC 2002; 39 (supplement A): 286A: 52A

76.              Malinin AI, Callahan KP, McKenzie ME, Serebruany VL. Effect of a Single Dose of Aspirin (325 mg) on Platelets in Human Volunteers With Multiple Risk Factors for Coronary Artery Disease. JACC 2002; 39 (supplement A): 260A.

77.              Serebruany VL, Steinhubl SR, Malinin AI, Callahan KP, Gurbel PA. Statins in General and Atorvastatin in Particular Do Not Affect Platelet Inhibition with Clopidogrel During Coronary Stenting. WCC-2002, Sydney, ESC Berlin 2002, and ACC 2003, Chicago

78.              Bahr RD, Gurbel PA, Malinin AI, Christenson RH, Roe MT, Gibler WB, Kitt M, EM Ohman, Serebruany VL for the EARLY Trial Investigators Correlation of Platelet Activation and Myocardial Ischemia Biomarkers Dependent on a Chest Pain Onset: Does Prodroma Matters? European Congress of Cardiology, AHA, 2002

79.              Serebruany VL, Glassman AH, Malinin AI, Krishnan RR, Gurbel PA, O’Connor CM. Platelet/Endothelial Activation in Depressed Patients after Acute Myocardial Infarction and Unstable Angina: Evidence from Clinical Trials. Ibid

80.              Serebruany VL, Glassman AH, Malinin AI, Sane DC, O'Connor CM. Selective Serotonin Reuptake Inhibitors Yield Additional Antiplatelet Benefit in Patients with Heart Failure Treated with Antecedent Aspirin. Ibid, and AHA 2002

81.              Serebruany VL, Malinin AI, Sane DC. The risk of bleeding complications with antiplatelet agents: a meta-analysis of 338,191 patients enrolled in 50 randomized controlled trials. AHA 2002 and Amer Neurol Assoc Meeting, New York 2002; AHA2002; ESC2003

82.               Serebruany VL, Malinin AI, Sane DC. Rapid platelet inhibition after a single pill of Aggrenox®: Challenging a conventional full-dose aspirin antiplatlet advantage? ANA  2002

83.              Serebruany VL, Malinin AI, O’Connor CM, Gurbel PA. Effect of roxifiban on platelet aggregation and major receptor expression in patients with coronary artery disease (The ROCKET-I Platelet Study). Berlin 2002, and AHA 2002

84.              Serebruany VL, Malinin AI, Lowry DR, Gottlieb SO, Sane DC, HennekensCH. Platelet Inhibition by Valsartan and Valeryl 4-hydroxy Valsartan: A Possible Missing Link to Explain Benefits of Angiotensin II Receptor Blockers in Patients After Acute Vascular Events. ACC – 2003; ISTH XIX congress, Birmingham, UK; and ESC (Vienna, 2003)

85.              Serebruany VL, Malinin AI, Jerome SE, Morgan AW, Lowry DR, Sane DC, O’Connor CM. Effects of clopidogrel-aspirin combination versus aspirin alone on platelet aggregation and major receptor expression in patients with heart failure. For the PLavix Use for Treatment Of Congestive Heart Failure (PLUTO-CHF) Trial ACC-2003.

86.              Gurbel PA, Gattis WA, Fuzaylov SF, Gaulden L, Hasselblad V, Serebruany VL, O'Connor CM. Evaluation of Platelets in Heart Failure: Is Platelet Activity Related to Etiology, Functional Class, or Clinical Outcomes? ACC-2003.

87.              Gurbel PA, Bahr RD, Roe MT, Serbruany VL, Malinin AI, Gibler WB, Ohman EM. EARLY Platelet Substudy. ACC-2003

88.              Serebruany VL, Malinin AI, Jerome SD, Morgan AW, Lowry DR, Sane DC, Steinhubl SR, Tanguay J-F, O’Connor CM. Effect of Clopidogrel and Aspirin Combination versus Aspirin Alone on Platelet Aggregation and Major Receptor Expression in Patients with Heart Failure. The Plavix Use for Treatment Of CHF (PLUTO-CHF trial). Ibid.

89.              Serebruany VL, Midei MG, Malinin AI, Oshrine BR, Lowry DR, Sane D, Tanguay JF, Steinhubl SR, Berger PB, O'Connor CM, Hennekens CH.  Absence of Interaction Between Atorvastatin and Clopidogrel in Prospective Data:  The Interaction of Atorvastatin and Clopidogrel (INTERACTION Study). ESC (Vienna, 2003); TCT (Washington, DC, 2003);  AHA (Orlando, 2003).

90.              Serebruany VL, Suckow RF, Cooper TB, Glassman AH, Malinin AI, Krishnan RR, Lekht V, Harrison W, Clary CM, O’Connor CM for the SADHART trial. Release of Platelet/Endothelial Biomarkers Negatively Correlates with the Plasma Levels of Sertraline and N-Desmethylsertraline in Depressed Patients After Acute Coronary Syndromes Treated with Selective Serotonin Reuptake Inhibitor. AHA (Orlando, 2003)

91.              Saw J, Steinhubl S, Berger P, Kereiakes D, Serebruany V, Brennan D, Topol E. Lack of clinical evidence of clopidogrel – atorvastatin interaction in a randomized, controlled clinical trial. Ibid

92.              Serebruany VL, Malinin AI, Sane DC, Takserman A, Atar D, and Hennekens CH. Magnitude and time course of platelet inhibition with Aggrenox and aspirin in patients after ischemic stroke. The AGgrenox versus Aspirin Therapy Evaluation (AGATE) Trial. Ibid, and 29th Stroke Congress (San Diego, 2004).

93.              Malinin A, Spergling M, Muhlestein B, Steinhubl S, Serebruany V. Detection of aspirin resistance in subjects with multiple risk factors for cardiovascular disease. Am Coll Cardiol 2004.

94.              Serebruany VL, Hanley D. Lack of phasic rebounds with Aggrenox in post-stroke patients: The core laboratory experience from the recent antiplatelet trials (EuroStroke-2004, Mannheim, Germany; and 5th World Stroke Congress, Vancouver, Canada, 2004).

95.              Serebruany VL, Malinin AI, Sane DC. The in vitro effects of dipyridamole on platelet activation, annexin-V binding, and thrombin generation: Overcoming aspirin resistance with Aggrenox? (EuroStroke-2004, Mannheim, Germany; and 5th World Stroke Congress, Vancouver, Canada, 2004).

96.              Serebruany VL, Steinhubl SR, Berger PB, Bhatt DL, Michelson AD, Topol EJ. Variability in Platelet Responsiveness to Clopidogrel Among 544 Individuals. Europ Congress of Cardiology, Munich, Germany, 2004, TCT, Washington, DC, 2004, Amer Heart Assoc, New Orleans, 2004.

97.              Serebruany VL,  Oshrine BR, Malinin AI, Sane DC, Takserman A, Atar D, Hennekens CH. Lack of the uniformed platelet activation in patients after ischemic stroke: Does aspirin matters? Ibid.

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